https://journals.accscience.com/index.php/itps/issue/feed INNOSC Theranostics and Pharmacological Sciences 2023-08-03T22:56:30+08:00 ITPS Editor editor.itps@accscience.com Open Journal Systems https://journals.accscience.com/index.php/itps/article/view/417 Precision medicine in neurosurgery: The evolving role of theranostics 2023-08-03T22:56:30+08:00 Drashti Patel drashti.patel@ufl.edu Andrew Nguyen andrewnguyen@ufl.edu Chance Fleeting cfleeting@ufl.edu Anjali Patel anjalipatel@ufl.edu Mohammed Mumtaz mmumtaz@ufl.edu Brandon Lucke-Wold brandon.lucke-wold@neurosurgery.ufl.edu <p>Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treatment. One such form of theranostics is focused ultrasound, which has been found to be effective in inducing neuroablation and neuromodulation and improving the efficacy of chemotherapy drugs by disrupting the blood–brain barrier. Targeted radionuclide therapy, which pairs positron emission tomography tracers with therapeutic effects and imaging modalities, is another promising form of theranostics for neurosurgery. Automated pathology analysis is yet another form of theranostics that can provide real-time feedback during the surgical resection of tumors. Electrical stimulation has also shown promise in optimizing therapies for patients with cerebral palsy. Overall, theranostics is a cost-effective way to optimize medical care for patients in neurosurgery. It is a relatively new field, but the advancements made so far show great promise for improving patient outcomes.</p> 2023-08-03T14:46:08+08:00 Copyright (c) 2023 Author(s)